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  5. Our Edge in IVF

Our Edge in IVF

  • IVF Success Rates

    The Mount Elizabeth Fertility Centre (MEFC) philosophy is to treat all patients with the goal to succeed. After discussing your personal history and performing tests, we provide clear and realistic information about your individual chances of fertility success. We do not reject patients with a low likelihood of success such as low responders or older women.

    At Mount Elizabeth Fertility Centre, our IVF success rates are a testament to our expertise and upholding of high standards in the field of fertility treatment, clinical embryology and laboratory technology. We pride ourselves in continually striving to improve by familiarising ourselves with more advanced in vitro fertilisation (IVF) techniques. The breakdown of MEFC success rates in IVF based on the age of the patients can be seen below.

    Age
    Fresh
    Thawed
    Clinical Pregnancy
    Rate1
    (2015 & 2016)
    Live Birth
    Rate 2
    (2015 & 2016)
    Clinical Pregnancy
    Rate1
    (2015 & 2016)
    Clinical Pregnancy
    Rate 1, 3
    (2017)
    Clinical Pregnancy
    Rate 1, 3
    (2018)
    Live Birth
    Rate 2
    (2015 & 2016)
    <30 80% 80% 65% 75% 82% 48%
    30–34 30% 30% 63% 76% 58% 56%
    35–39 35% 28% 43% 55% 56% 32%
    40–44 26% 12% 38% 42% 47% 17%
    <40 34% 30% 54% 65% 59% 44%
    Total 32% 25% 51% 59% 56% 39%
                 
     20183 Fresh
    		 Thawed
    Total N/A 56%
  • 1Pregnancy rate refers to the number of pregnancies over the number of embryo transfers
     2Live birth rate refers to the number of live birth events over the number of embryo transfers
     3Results are reported as ongoing pregnancies per embryo transfer
    Your success rate can be affected by factors such as your age and weight, and the causes of infertility and individual results will vary.
    Not every treatment cycle will result in an egg retrieval, an embryo transfer or embryo/blastocyst vitrification.
    For more information on how to interpret IVF success rates, you can refer to information from the Human Fertilisation and Embryology Authority (HFEA).

  • The above results are based on the Mount Elizabeth Fertility Centre ethos of not specifically selecting the patients we treat.

    In the data provided by the Human Fertilisation and Embryology Authority (HFEA), 11% of cycles are in women with low ovarian/egg reserves (low responders). At Mount Elizabeth Fertility Centre, 23% of our cycles are performed on women with low ovarian/egg reserves, and 40% of our treatment cycles are performed on patients who are either low responders or aged 40 years old and above.

    This shows that many of the cases we treat are complicated, and our consistent success rates are a testament to our expertise in fertility treatment.

  • Factors that Optimise Chances of IVF Success

    pregnant woman

    At Mount Elizabeth Fertility Centre, we are committed to providing comprehensive care and treatment with the greatest chances of success. We adopt and constantly familiarise ourselves with the latest technologies and protocols while upholding stringent quality control and laboratory standards. We attract skilled and experienced fertility specialists into our team, and are dedicated towards continuous improvement and learning to provide excellent clinical outcomes.

    We partner with experts in the assisted reproductive technology (ART) field, such as Dr Mashashige Kuwayama, the head of Tokyo-based Repro-support Medical Research Centre and the inventor of the renowned Cryotec/Cyrotop method. This is a technique that allows even safer and more efficient vitrification (freezing) of eggs and embryos at a 100% survival rate. Mount Elizabeth Fertility Centre has been vitrifying embryos since year 2007.

  • Advanced IVF Technologies

    Advanced blastocyst culture system and transfer, the double stimulation protocol, and blastocyst vitrification (freeze all IVF) are 3 advances in IVF technology that have greatly increased the number of live births in each stimulated IVF cycle, and have been routinely practised at Mount Elizabeth Fertility Centre since 2002.

    Blastocyst Culture

    fertilisation in IVF laboratory

    Advances in blastocyst culture and transfer have resulted in improved IVF pregnancy rates and reduced multiple births. At Mount Elizabeth Fertility Centre, our high laboratory standards with good culture conditions allows us to best support the growth of embryos to the blastocyst stage, where we are able to select the healthiest embryos with the highest potential for implantation (those that are most likely to attach to the uterine wall and develop into a healthy pregnancy).

    Only 1 or 2 blastocysts will be selected for transfer back to the mother, compared to the traditional 3 or 4 early-stage embryos, thus optimising chances of a successful pregnancy while minimising the risk of multiple births.

    Our chief embryologist, Ms Ng Lai Cheng has been culturing blastocysts since 1993, first as part of a pioneering animal research co-culture team in blastocyst culture and transfer and later on in clinical embryology.

    Double Stimulation

    In classic IVF procedures, only 1 oocyte retrieval (egg collection) is performed using mild ovarian stimulation during the early follicular phase. The double stimulation protocol is where a 2nd oocyte retrieval is performed during luteal-phase stimulation. This allows the retrieval of more oocytes. Retrieval of more oocytes allows for better chances in obtaining quality blastocysts and therefore higher pregnancy success rates. The double stimulation protocol is especially beneficial for women who are poor ovarian responders, which could be due to factors such as low ovarian reserves or older age.

    Freeze-all Blastocysts Strategy

    vitrification of blastocysts in freeze all IVF

    At Mount Elizabeth Fertility Centre, we routinely apply an advanced laboratory technique known as freeze-all IVF. Vitrification is one of the most effective methods for the successful freezing of blastocysts, allowing for improved post-thaw embryo survival and substantially higher pregnancy rates. The freeze-all blastocysts strategy is especially beneficial for women who are diagnosed with low ovarian reserves or women who encounter poor ovarian response during IVF treatment.

    Women of advanced maternal age, or even cancer patients who wish to preserve their fertility prior to undergoing gonadotoxic (having a harmful effect on reproductive glands) cancer therapy, may also choose to benefit from this procedure.

    Talk to your fertility specialist to understand more about IVF treatment and our protocols.

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