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Allogeneic Transplant

  • What is an Allogeneic Transplant?

    “Allo” in allogeneic means “other” which means that the stem cells come from another person (donor) whose genetic typing matches yours. The donor is usually directly related to you like your brother or sister. Special blood tests are done to check for donor-recipient compatibility.

    In some cases, if you don’t have a good match in your family, compatible donors may be found through the international bone marrow registries. Also, blood from the umbilical cords of newborns have been used as a source of stem cells and used mainly for treatment of children (as the number of stem cells in this blood is not enough to treat adults).

  • Allogeneic transplant is a type of stem cell transplant used to treat:

    • Leukaemia (cancer of the blood)
    • Other bone marrow disorders


    • The donor stem cells produce their own immune cells, which may help destroy the cancer cells that remain after high-dose treatment.
    • The donor can be recalled to donate more stem cells if needed.


    • The donor cells may be more likely to die or be destroyed by the recipient’s immune system before settling in the bone marrow.
    • The donor cells may create new immune cells that attack the recipient’s body, a condition known as graft-versus-host disease (GVHD).
    • A small risk of infections from the donor cells (although donors are tested beforehand to minimise this risk).
  • Our skilled team of specialists and staff operate at Mount Elizabeth Orchard and Mount Elizabeth Novena – both award-winning hospitals with modern technology and facilities.

    Take your first step towards better health today, and experience the quality and customised healthcare that has made us one of the leading medical institutions in Asia-Pacific.

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