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Living Donor Liver Transplant

  • What is Living Donor Liver Transplant (LDLT)?

    Living donor liver transplant (LDLT) is an important life-saving procedure for patients suffering from acute liver failure and hepatocellular carcinoma. It can be performed on any patient with end-stage liver disease regardless of the original cause of the disease.

    • In LDLT, a healthy live donor donates part of his/her healthy liver to replace the damaged liver of the recipient.
    • The donor’s liver and the part of the donor’s liver transplanted into the recipient will regenerate themselves and grow back to their full size.
    • LDLT offers many advantages over cadaveric liver transplantation. The surgery can be scheduled when the recipient is as healthy as possible, and the quality of the transplant is better because it is provided by a healthy donor. Most importantly the waiting time for LDLT is much shorter than cadaveric liver transplant, which is crucial for patients with rapidly progressive liver diseases.
  • LDLT can be the last option for patients with end-stage liver disease. In adults, the most common reason for LDLT is liver cirrhosis, which refers to scarring of the liver. Liver cirrhosis is mainly caused by Hepatitis B and C, chronic alcohol consumption, autoimmune liver disease and accumulation of fat in the liver. In children, biliary atresia is the most common reason for LDLT.

    Biliary atresia is caused by an absent or a blocked bile ducts, which are tubes that carry bile out of the liver. The bile then backs up and damages liver tissue, and eventually leads to cirrhosis.

    Other reasons for LDLT include liver cancer, benign (non-cancerous) liver tumours, and hereditary liver diseases.

  • Your goal of getting swift, accurate and effective treatment is our strength. Our skilled team of specialists and staff operate at Mount Elizabeth Orchard and Mount Elizabeth Novena – both award-winning hospitals with advanced technology and modern facilities. Take your first step towards better health today, and experience the high-quality, customised healthcare that has made us one of the leading medical institutions in Asia-Pacific.

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